Trials / Recruiting
RecruitingNCT05986461
Spatially Transcriptomics Reveals Molecular Signatures in CRPS
Spatially Resolved Transcriptomics Reveals Phenotype-specific Molecular Signatures in Complex Regional Pain Syndrome
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 10 (estimated)
- Sponsor
- Seoul National University · Academic / Other
- Sex
- All
- Age
- 19 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This observational study aims to understand phenotype-specific molecular signatures in patients with complex regional pain syndrome (CRPS).
Detailed description
Participants who meet the diagnostic criteria for CRPS, aged 19\~80 years, and agree to participate in this study will undergo a 4mm-sized skin punch biopsy in the involved limb, as well as the contralateral side (internal control). Spatial transcriptomics will be used to identify immune cell signatures and differentially regulated genes (DEGs) in the epidermis, vasculature, sweat gland, and nerve plexus of the involved ipsilateral (vs contralateral) side of the patient's skin.
Conditions
Timeline
- Start date
- 2023-07-18
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
- First posted
- 2023-08-14
- Last updated
- 2024-05-29
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT05986461. Inclusion in this directory is not an endorsement.