NCT05985473

Real-time Artificial Intelligence-based Speech Enhancement Methods for Hearing Aid Improvement

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Institut Pasteur · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Individuals with Auditory Neuropathy Spectrum Disorders (ANSD) represent 1-10% of adults with hearing loss. These individuals have little or no benefit from current hearing aids because ANSD is a continuum of hearing impairments due to synaptic or neural dysfunction in the peripheral and central parts of the auditory pathways, which impairs temporal information processing without necessarily affecting auditory sensitivity. There is a need to find ad-hoc denoising methods, based on the expert knowledge of audiologists, to improve the noise comprehension performance of these patients. Implemented denoising methods, based on artificial intelligence, will also greatly benefit more standard hearing loss cases.

Detailed description

Longitudinal study consisting of multiple visits with multiple examinations over a total duration of approximately 3 years per ANSD participant and 1 year per normal hearing participant. * normal hearing participant : year 1 : Inclusion visit, Phenotyping visit (Audiological tests), Follow-up Visit 1 (Noise Comprehension Tests) * ANSD participant : year 1 : Inclusion visit, Phenotyping visit (Audiological tests), Follow-up Visit 1 (Noise Comprehension Tests) year 2 : Follow-up Visit 2 (Noise Comprehension Tests) year 3 : Follow-up Visit 3 (Noise Comprehension Tests)

Conditions

• Deafness Neurosensory

Interventions

Type	Name	Description
OTHER	audiological measurements	audiological measurements
OTHER	Objective and subjective audiological measurements	Objective and subjective audiological measurements
OTHER	Evaluation of the denoising methods REFINED	Evaluation of the denoising methods REFINED

Timeline

• Start date: 2024-03-06
• Primary completion: 2026-09-15
• Completion: 2026-09-15
• First posted: 2023-08-14
• Last updated: 2024-03-15

Locations

1 site across 1 country: France