NCT05984069

Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS). Other complications have been described, including ICU-acquired weakness, leading to increased morbidity and mortality after discharge. Actually, risk factors associated with post-ICU fatigue self-reported are not really known.

Detailed description

Frailty, defined as a decrease in physiological reserves leading to an alteration in the mechanisms of adaptation to stress, increases the incidence of PICS and could therefore be a cause of post-ICU fatigue self-reported. The aim of this study is to identify a relationship between markers of frailty, ICU-AW, ICU story and the post-ICU fatigue self-reported 6 months discharge in patients with prolonged ICU stays.

Conditions

• Post Intensive Care Syndrome

Interventions

Type	Name	Description
OTHER	observational prospective data collection	Collection of data from medical records.

Timeline

• Start date: 2022-07-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2023-08-09
• Last updated: 2025-03-18

Locations

2 sites across 1 country: France