NCT05983081

Efficacy of Intra-articular Hyaluronate Injection for Adhesive Capsulitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Tri-Service General Hospital · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Objective: To evaluate the efficacy of intra-articular hyaluronic acid (HA) injections for the treatment of adhesive capsulitis (AC) of the shoulder. Design: Prospective, randomized, parallel-group interventional trial Setting: Rehabilitation department of a medical center hospital. Participants: Participants: Patients with frozen-phase primary adhesive capsulitis Interventions: The patients received intra-articular glenohumeral joint injections of HA, 60mg, once per week for 3 consecutive weeks. Main Outcome Measures: Active and passive range of motion (ROM) of the affected shoulder; Shoulder pain and disability were measured using 2 questionnaires: the SPADI. The patients were evaluated before treatment and were reevaluated 4, 6, 8, and 26 weeks after the beginning of the treatment.

Conditions

• Adhesive Capsulitis

Interventions

Type	Name	Description
DRUG	hyaluronic acid	patients receives intra-articular injections of Hyaluronic acid. the injections were administered once a week for three consecutive weeks, total three injections per patients
OTHER	Physical Therapy	a week physical therapy program, consist of two sessions per week, (30 minutes each), including joint exercises, stretch and etc..

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-08-14
• Completion: 2024-08-14
• First posted: 2023-08-09
• Last updated: 2026-03-11

Locations

1 site across 1 country: Taiwan