NCT05982015

Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia

Multicenter, Randomized, Double-blind, Pseudo Treatment-controlled Clinical Study on the Efficacy and Safety of Remote Ischemic Conditioning in Preventing Stroke-associated Pneumonia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,651 (actual)
• Sponsor: Capital Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Verifying whether remote ischemic adaptation can reduce the occurrence of stroke related pneumonia in acute stroke patients within 24 hours of onset

Detailed description

Verifying whether remote ischemic adaptation can reduce the occurrence and safety of stroke related pneumonia in acute stroke patients within 24 hours of onset

Conditions

• Stroke

Interventions

Type	Name	Description
DEVICE	Remote ischemic conditioning	The RIC procedure consists of five cycles of unilateral arm ischemia for 5 minutes, which was followed by reperfusion for another 5 minutes. The procedure is performed with an electric, autocontrol device with a cuff that inflated to a pressure of 200 mmHg during the ischemia period. RIC is performed within 24hours after stroke onset, and twice daily for the subsequent 7 days.
DEVICE	Sham remote ischemic conditioning	The RIC procedure consists of five cycles of unilateral arm ischemia for 5 minutes, which was followed by reperfusion for another 5 minutes. The procedure is performed with an electric, autocontrol device with a cuff that inflated to a pressure of 60 mmHg during the ischemia period. RIC is performed within 24hours after stroke onset, and twice daily for the subsequent 7 days.

Timeline

• Start date: 2024-01-22
• Primary completion: 2024-09-19
• Completion: 2024-12-19
• First posted: 2023-08-08
• Last updated: 2024-12-27

Locations

1 site across 1 country: China