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Trials / Completed

CompletedNCT05981976

A Study to Evaluate the Drug Levels of Abatacept Converted From Drug Substance by Two Different Processes in Healthy Participants

A Randomized, Open-Label, Parallel-Group, Single-dose, Relative Bioavailability Study of the Pharmacokinetics of Subcutaneous Abatacept (BMS-188667) Drug Product Converted From Drug Substance of a New Abatacept Drug Substance Process J Relative to the Current Abatacept Drug Process F in Healthy Participants

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
174 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to compare the relative absorption of abatacept in healthy participants following subcutaneous (SC) administration in which the drug substance is manufactured with the current or new process.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAbataceptSpecified dose on specified days

Timeline

Start date
2023-08-18
Primary completion
2023-12-14
Completion
2023-12-14
First posted
2023-08-08
Last updated
2024-07-29

Locations

3 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05981976. Inclusion in this directory is not an endorsement.

A Study to Evaluate the Drug Levels of Abatacept Converted From Drug Substance by Two Different Processes in Healthy Par (NCT05981976) · Clinical Trials Directory