Trials / Active Not Recruiting
Active Not RecruitingNCT05977699
Reversibility of Methacholine Induced Bronchoconstriction
Salbutamol Reversal of Methacholine Induced Bronchoconstriction: Vibrating Mesh Nebulizer Versus Pressurized Metered Dose Inhaler
- Status
- Active Not Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- University of Saskatchewan · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The study will compare salbutamol reversibility of methacholine induced bronchoconstriction between a pressurized metered dose inhaler with a spacer versus nebulizer administration using a vibrating mesh nebulizer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | salbutamol aqueous solution | administration of 200microliters of salbutamol to reverse methacholine induced bronchoconstriction using a vibrating mesh nebulizer |
| DRUG | salbutamol pressurized metered dose inhaler | administration of 200microliters of salbutamol to reverse methacholine induced bronchoconstriction using a pressurized metered dose inhaler plus spacer |
| OTHER | placebo | matching placebo delivered via pressurized metered dose inhaler plus spacer or normal saline via vibrating mesh nebulizer |
Timeline
- Start date
- 2024-01-12
- Primary completion
- 2024-12-30
- Completion
- 2024-12-30
- First posted
- 2023-08-04
- Last updated
- 2024-12-06
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT05977699. Inclusion in this directory is not an endorsement.