NCT05977543

Acute Effect of Functional Crackers on Postprandial Metabolism

The Acute Effect of Functional Crackers, Enriched With Grape Seed Flour or With Barley Flour and β-glucans, on Postprandial Glycemic, Lipemic and Antioxidant Metabolism

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: University of the Aegean · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this interventional study was to investigate the postprandial effect of two types of functional crackers, with 10% grape seed flour or 40% barley flour, enriched with β-glucan, in metabolic biomarkers of healthy participants.

Detailed description

A pilot cross-over, controlled, randomized and single-blinded, intervention-clinical trial was carried out, in twelve healthy men and women, aged nineteen to sixty-five years, after random allocation into the control, the grape and the barley interventional groups, received a high-fat and high-carbohydrate meal, containing wheat flour or wheat and 10% grape seed flour or wheat and 40% barley flour, enriched with β-glucan, crackers. Participants consumed the same meals, allocating in cross-over order, with 1 washout week after each trial period. Differences on the metabolism of postprandial serum total, High Density Lipoprotein (HDL-), Low Density Lipoprotein (LDL-) cholesterol, glucose, triglycerides and uric acid levels, as well as of plasma total antioxidant capacity according to Ferric Reducing Antioxidant Power method, were determined between groups in fasting, thirty minutes, one and a half hour, and three hours after meal intake.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Functional crackers enriched with grape seed flour	The crackers was enriched with 10% grape seed flour
OTHER	Functional crackers with 40% barley flour and enriched with β-glucans	The crackers consisted of 60% wheat flour, 40% barley flour and was enriched with β-glucans.

Timeline

• Start date: 2023-02-15
• Primary completion: 2023-10-01
• Completion: 2024-01-15
• First posted: 2023-08-04
• Last updated: 2023-11-30

Locations

1 site across 1 country: Greece