NCT05977387

Pediatric Kidney Transplant

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Imagine Institute · Academic / Other
• Sex: All
• Age: 0 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

End-stage renal disease (ESRD) is a rare disease in children. Renal transplantation (RT) is the treatment of choice for ESRD in the pediatric population. In France, around 100 pediatric kidney transplants are performed each year. The aim was to evaluate the surgical management of TR and the long-term results.

Detailed description

End-stage renal disease (ESRD) is a rare pathology in children, whose gold standard treatment is a kidney transplant. In France, around 100 pediatric kidney transplants are performed every year. Although the first adult kidney transplants were performed in 1954, pediatric renal transplantation was considered unsafe compared with dialysis, which was preferred. In the 1980s, improved graft selection, optimized pre-transplant management and a better understanding of the immune system led to the development of pediatric kidney transplantation. Despite considerable progress, graft survival in these long-lived patients remains a major challenge. The aim of this study is to evaluate surgical practices in the four French pediatric transplant centers, and to define risk factors for surgical complications.

Conditions

• End Stage Renal Disease
• Pediatric ALL
• Kidney Transplant; Complications

Timeline

• Start date: 2021-10-01
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2023-08-04
• Last updated: 2023-08-04

Locations

4 sites across 1 country: France