NCT05977231

Efficacy of Conservative Treatments for Urinary Incontinence in Women

Evaluation of Efficacy of Conservative Treatments in Women With Urinary Incontinence

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Mackay Medical College · Academic / Other
• Sex: Female
• Age: 20 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

To conduct a retrospective study to examine the effect of these conservative treatments to the symptoms and quality of life of patients with urinary incontinence. The investigators will use both subjective and objective assessment parameters, such as self-report symptoms, bladder diary, pad test and urodynamic study to access the improvement.

Detailed description

Urinary incontinence is a common problem among women. The main types include stress incontinence, urge incontinence, and overflow incontinence. Other underlying pathology, such as cancer or neurologic disease can also cause urinary incontinence. To limit the medical expenses and possible complications of surgical treatment, the current treatment guidelines recommend conservative treatment as the first choice. According to American Urological Association (AUA)/Society of Urodynamics, Female Pelvic Medicine \& Urogenital Reconstruction (SUFU) guidelines, the first-line treatment for non-neurologic overactive bladder should be behavioral therapy, such as bladder training, water restriction, and pelvic floor muscle training, physiological feedback, pessary, etc. Bladder training aims to increase the time interval between voids, and to increase the bladder capacity by self-adjusted schedules. Pelvic floor muscle training strengthens the pelvic floor muscles to provide urethral support to prevent urine leakage and suppress urgency. There is strong evidence that pelvic floor muscle training is beneficial for stress urinary incontinence. The second-line treatment is medication, including anticholinergic drugs and ß3 adrenoceptor-acting agents. Anticholinergic drugs can reduce bladder detrusor contraction, and ß3 adrenoceptor-acting agents can relax the detrusor and increase bladder capacity.

Conditions

• Urinary Incontinence

Interventions

Type	Name	Description
PROCEDURE	BT	A program of BT (including exercise and muscle training)
PROCEDURE	bPFMT	A bPFMT program at home
PROCEDURE	iVES	An iVES program at home
PROCEDURE	BT + bPFMT	Combination of BT and bPFMT
PROCEDURE	BT + iVES	Combination of BT and iVES
PROCEDURE	bPFMT + iVES	Combination of bPFMT and iVES

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-12-31
• Completion: 2028-12-31
• First posted: 2023-08-04
• Last updated: 2023-08-04

Locations

1 site across 1 country: Taiwan