NCT05975346

Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 16 Years – 60 Years
• Healthy volunteers: —

Summary

Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness. Patients rated postoperative sore throat (POST) as the eighth most undesirable outcome in the postoperative period POST has a reported incidence of up to 62% following general anesthesia (GA). The incidence of POST is more common in GA with tracheal intubation than in GA with the supraglottic airway Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist and has been used as a gargle for reducing the incidence and severity of POST due to its anti-nociceptive and anti-inflammatory effects

Conditions

• Post Operative Sore Throat

Interventions

Type	Name	Description
DRUG	Ketamine	description
OTHER	saline nebulization	description

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-01-01
• Completion: 2024-01-01
• First posted: 2023-08-03
• Last updated: 2023-08-03