NCT05975086

Right Ventricle Dysfunction in Critically Ill Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: —

Summary

To assess prevalence of right ventricle dysfunction in critically ill patient. To assess impact of RV dysfunction on short term (ICU stay, hospital stay, or mortality ≤30 days) and long term outcome (\>30 days). To assess the accuracy of different parameters of RV dysfunction.

Detailed description

1. Inclusion criteria: \- Adult patients who admitted to critical care of Internal medicine department after obtaining consent during the period between august 2023 and august 2024. 2. Exclusion criteria: 1. Children below 18 yr. 2. Patients who could not be scanned within 48h after ICU admission. 3. Sample Size Calculation: 200 patients 2.4.4 Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, ): Beside history and clinical examination , The following data will be obtained: Demographic and historical data: the patient age, sex, history of hypertension, chronic obstructive pulmonary disease, IHD, cause of critical care unit admission and indication of mechanical ventilation( PEEP). Clinical examination data: pulse, blood pressure, respiratory rate, temperature , BMI, and thorough chest, cardiac examination data will be obtained. Volume state of the patient: CVP measurement, input and output fluid chart. APACHE IV score, Use of vasopressors, Use of sedatives. Investigation : Arterial blood gas analysis, pulse oxygen saturation, CBC, and renal function test and electrolytes, serum lactate and troponin. 12 lead ECG for RV strain patterns.

Conditions

• Right Ventricular Dysfunction

Timeline

• Start date: 2023-08-30
• Primary completion: 2024-08-01
• Completion: 2024-09-01
• First posted: 2023-08-03
• Last updated: 2023-08-03