NCT05975034

Investigation of the Use of a Probiotic Supplement in People With Long COVID

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Sheffield Hallam University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is a double-blinded randomised trial to assess the efficacy of a probiotic supplement in alleviating symptoms in people with Long COVID.

Detailed description

240 participants with Long COVID will be randomly assigned to either a probiotic or placebo group in a 1:1 ratio for twelve weeks. Participants will track symptoms using an app for three weeks before the study, and for the last three weeks of the treatment. Participants will answer online questionnaires about their symptoms at 0, 4, 8, and 12 weeks. A subgroup of 60 participants will attend the laboratory for blood tests, cognitive function tests and gut microbiome analysis at 0 and 12 weeks. This group will also wear activity trackers for two weeks before the study, and for the final two weeks of the study.

Conditions

• Long COVID

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	Probiotic taken daily for 12 weeks.
DIETARY_SUPPLEMENT	Placebo	Placebo taken daily for 12 weeks.

Timeline

• Start date: 2023-06-12
• Primary completion: 2023-12-11
• Completion: 2023-12-11
• First posted: 2023-08-03
• Last updated: 2023-08-03

Locations

1 site across 1 country: United Kingdom