NCT05974813

The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: European University Cyprus · Academic / Other
• Sex: Male
• Age: 55 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to examine the effect of short-term L-Citrulline on central and peripheral blood pressure in healthy older adults. The main questions it aims to answer are: * Does L-citrulline favorably affect blood pressure at rest and during exercise? * Does L-citrulline favorably affect arterial stiffness? * Does L-citrulline favorably affect muscle oxygenation at rest and during exercise? Participants will be asked to consume L-citrulline and a placebo for six days and participate in the evaluation of their blood pressure, arterial stiffness, and muscle oxygenation before and after each intervention. Researchers will compare L-citrulline and placebo groups to examine whether L-citrulline supplementation affects the above health parameters.

Conditions

• Blood Pressure

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	L-Citrulline	6 g (3 g every 12 h) of L-citrulline for six days
DIETARY_SUPPLEMENT	Placebo	6 g (3 g every 12 h) of maltodextrin for six days

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-03-01
• Completion: 2023-03-01
• First posted: 2023-08-03
• Last updated: 2023-08-03

Locations

1 site across 1 country: Cyprus