NCT05973019

rTMS Improves Functions in Spinocerebellar Ataxia

Repetitive Transcranial Magnetic Stimulation Improves Functional Performance in Spinocerebellar Ataxia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Changhua Christian Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Spinocerebellar ataxia (SCA) is a group of inherited brain disorders. SCA often result in poor limb coordination. This study aims to discover the effects of repeated transcranial magnetic stimulation (rTMS) on balance \& gait in SCA. The hypothesis of this study is that rTMS might improve SCA limb functional performance.

Detailed description

rTMS has been shown that improves walking speed and balance performance, however, the optimal treatment protocols have not been approved. Past studies used different frequencies 1 Hz, 5 Hz and 10 Hz to improve functional performance. The results might be affected by the types of SCA. In this study, we will focus on the SCA type 3 to assess the effects on high frequency (10 Hz) of rTMS intervention.

Conditions

• Transcranial Magnetic Stimulation
• Spinocerebellar Ataxias

Interventions

Type	Name	Description
DEVICE	Repetitive Transcranial Magnetic Stimulation (rTMS)	6 times/per week for 2 weeks, total 12 times rTMS with 10 Hz.

Timeline

• Start date: 2023-09-01
• Primary completion: 2024-06-30
• Completion: 2024-08-01
• First posted: 2023-08-02
• Last updated: 2023-10-18

Locations

2 sites across 1 country: Taiwan