Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT05972473

A Study to Evaluate the Efficacy and Safety of IBI302 in Subjects With nAMD

A Phase 3, Randomized, Double-masked, Active-Controlled Study to Evaluate the Efficacy and Safety of Intravitreal IBI302(Efdamrofusp Alfa) in Subjects With Neovascular Age-Related Macular Degeneration

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
600 (actual)
Sponsor
Innovent Biologics (Suzhou) Co. Ltd. · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The study is designed for multi-center,randomized,double-masked,active-contralled study to evaluate effective and security of intravitreal injection of IBI302 in subjects with neovascular age-related macular degeneration.

Conditions

Interventions

TypeNameDescription
DRUGAflibercept Ophthalmic2mg Aflibercept will be administered by intravitreal injection into the study eye once every 4 weeks for 3 consecutive monthes, folloesd by once every 8 weeks(Q8W).
BIOLOGICALIBI3028 mg IBI302 will be administered by intraitreal injection into the study eye at intervals as specified in the study protocol.

Timeline

Start date
2023-09-21
Primary completion
2027-02-28
Completion
2027-04-30
First posted
2023-08-02
Last updated
2025-03-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05972473. Inclusion in this directory is not an endorsement.