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Active Not RecruitingNCT05972278

Investigating the Effect of Obicetrapib on Lipoprotein Metabolism

A Placebo-Controlled, Phase 1 Study to Investigate the Effect of Obicetrapib on Lipoprotein Metabolism.

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
22 (actual)
Sponsor
NewAmsterdam Pharma · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Accepted

Summary

To determine the treatment effect with obicetrapib (10 mg) on the fractional catabolic rate (FCR) of apolipoprotein (apo) B100 in low-density lipoprotein (LDL).

Detailed description

The study population will comprise 20 adults, 18 to 75 years of age, with LDL-C level ≥ 100 and ≤ 190 mg/dL, and in generally good health.

Conditions

Interventions

TypeNameDescription
DRUGObicetrapib1 tablet daily

Timeline

Start date
2023-12-01
Primary completion
2024-09-26
Completion
2024-10-14
First posted
2023-08-02
Last updated
2024-09-19

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05972278. Inclusion in this directory is not an endorsement.