NCT05971264

Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University Children's Hospital, Zurich · Academic / Other
• Sex: All
• Age: 12 Months
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn more about intestinal regional oxygen saturation measurements made with near-infrared spectroscopy and bladder pressure measurements in infants without risk of intraabdominal hypertension. The main question it aims to answer is if - in comparison to bladder pressure - the regional intestinal oxygen saturation measured with near-infrared spectroscopy is stable in the muscle-relaxed, intubated patients and the awake and non-sedated patient. In case of participation the bladder pressure and the regional intestinal oxygen saturation (measured with near-infrared spectroscopy) will each be measured once intraoperatively and once postoperatively. Patients included in this study will be undergoing an operation which necessitates muscle-relaxation, as well as an indwelling urinary catheter during the operation and for a short-time thereafter for other reasons than this study.

Conditions

• Intraabdominal Hypertension
• Abdominal Compartment Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Near infrared-spectroscopy	Comparison of regional intestinal oxygen saturation (measured with near infrared-spectroscopy) and indirect intraabdominal pressure measurement (bladder pressure) in muscle-relaxed, sedated patients compared to awake, non-sedated patients.

Timeline

• Start date: 2024-05-01
• Primary completion: 2025-12-31
• Completion: 2026-06-30
• First posted: 2023-08-02
• Last updated: 2024-04-25

Locations

1 site across 1 country: Switzerland