NCT05969834

HCG Levels After Ovulation Triggering as Predictors of ICSI Outcome

Human Chorionic Gonadotropin Levels After Ovulation Triggering as Predictors of Intracytoplasmic Sperm Injection Outcome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Mansoura University · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to assess the correlation between HCG levels after ovulation triggering and ICSI outcomes, affected by HCG formulation and dose

Detailed description

The aims of this study are: 1. To assess the correlation between serum human chorionic gonadotropin (hCG) level after ovulation triggering and intracytoplasmic sperm injection (ICSI) outcome including: oocyte maturity and quality, good quality embryo rate, blastocyst formation rate and pregnancy rate 2. To determine if there is an association between type and dose of the trigger and ICSI outcome.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	uHCG	Final oocyte maturation will be triggered by IM administration of 10000 IU of uHCG (Choriomon)
DRUG	rHCG	Final oocyte maturation will be triggered by SC administration of 6500 IU of rHCG (Ovitrelle)
DRUG	uHCG and GnRHa	Final oocyte maturation will be triggered by combined SC administration of 0.1 mg of GnRHa (Decapeptyl, Triptorelin) and IM administration of 2500 IU of uHCG (Choriomon)

Timeline

• Start date: 2021-03-31
• Primary completion: 2022-07-19
• Completion: 2022-08-07
• First posted: 2023-08-01
• Last updated: 2023-08-01

Locations

1 site across 1 country: Egypt