NCT05965466

The Incidence of Gallstones After Gastrectomy

Effect of Gastric Cancer Surgical Resection Extent on Postoperative Gallstone Formation: A Retrospected Cohort Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 531 (actual)
• Sponsor: Hepatopancreatobiliary Surgery Institute of Gansu Province · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

To provide preventive and therapeutic strategies for participants with gallstones after gastric cancer by comparing the risk of postoperative gallbladder stone formation with two different resection ranges using the Roux-en-Y reconstruction modality in radical gastric cancer surgery.

Detailed description

A large number of clinical studies have found that the incidence of gallstones in patients after radical gastric cancer surgery is higher than that in the normal population. However, the pathogenesis has not been clarified, and the prophylactic removal of the gallbladder in patients with gastric cancer remains controversial. A previous study found a statistically significant incidence of gallbladder stones after Billroth I versus Roux-en-Y in distal gastrectomy for gastric cancer. Therefore, the investigators plan to conduct a retrospected cohort study to collect further participants with gastric cancer who underwent total gastrectomy to answer whether different surgical resection ranges during surgery increase the incidence of gallstones this question.

Conditions

• Gallstone
• Gastric Cancer

Interventions

Type	Name	Description
PROCEDURE	Distal gastrectomy and radical resection	Distal gastrectomy and Roux-en-Y anastomosis
PROCEDURE	Total gastrectomy and radical resection	Total gastrectomy and Roux-en-Y anastomosis

Timeline

• Start date: 2023-07-21
• Primary completion: 2024-11-16
• Completion: 2024-11-16
• First posted: 2023-07-28
• Last updated: 2024-11-19

Locations

2 sites across 1 country: China