Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05963347

Go-CHOP as the Frontline Therapy for PTCL

A Phase 2 Study to Investigate the Safety, Tolerability and Anti-tumor Activity of Golidocitinib in Combination With CHOP as the Front-line Treatment for Participants With Peripheral T-cell Lymphomas (PTCL)

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
45 (estimated)
Sponsor
Henan Cancer Hospital · Other Government
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a phase 2 Study to investigate the safety, tolerability, and anti-tumor activity of golidocitinib in Combination with CHOP as the front-line Treatment for Participants with Peripheral T-cell Lymphomas (PTCL).

Conditions

Interventions

TypeNameDescription
DRUGGolidocitinibDaily dose. Starting dose of golidocitinib is 75 mg QD. If tolerated, subsequent cohorts will test ascending doses of golidocitinib.
DRUGCHOP RegimenCHOP will be administered in a 21-day cycle for a maximum of 6 cycles.

Timeline

Start date
2023-08-03
Primary completion
2025-07-30
Completion
2026-07-31
First posted
2023-07-27
Last updated
2023-09-01

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05963347. Inclusion in this directory is not an endorsement.