Clinical Trials Directory

Trials / Enrolling By Invitation

Enrolling By InvitationNCT05962398

Long-term Follow-up Study of Male Adults With Hemophilia B Previously Treated With Etranacogene Dezaparvovec (CSL222)

An Extension Study Assessing the Long-term Safety and Efficacy of Etranacogene Dezaparvovec (CSL222) Previously Administered to Adult Male Subjects With Hemophilia B

Status
Enrolling By Invitation
Phase
Study type
Observational
Enrollment
56 (estimated)
Sponsor
CSL Behring · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to assess the long-term safety and efficacy in male adults with hemophilia B who were treated with CSL222 (CSL222) in parent studies CSL222\_2001 (NCT03489291) or CSL222\_3001 (NCT03569891).

Conditions

Interventions

TypeNameDescription
GENETICAAV5-hFIXco-PaduaSingle intravenous infusion of AAV5-hFIXco-Padua in the study CSL222\_2001 (NCT03489291) or CSL222\_3001 (NCT03569891).

Timeline

Start date
2023-08-30
Primary completion
2035-03-23
Completion
2035-03-23
First posted
2023-07-27
Last updated
2025-07-18

Locations

28 sites across 8 countries: United States, Belgium, Denmark, Germany, Ireland, Netherlands, Sweden, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT05962398. Inclusion in this directory is not an endorsement.