NCT05961475

Monitoring Postprandial Glycemia in Fruit Snacks

Evaluating the Postprandial Glucose Response After Fruit Snack Consumption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Ocean Spray Cranberries, Inc. · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare the postprandial glucose and insulin responses after different fruit snack consumption in a healthy population.

Detailed description

Fruit snacks made from sweetened dried fruits is a source of polyphenols, fiber, and other nutrients. The addition of sugar could aid in the taste, texture, and shelf life of these types of products. Fruit snacks with different levels of sugar were developed to meet various consumer needs. The postprandial glucose response in a healthy population is of interest in this regard. Mulberry leaf extract has been shown the benefit of blood glucose regulation in multiple studies. This is mainly due to the function of the most predominant iminosugar, 1-deoxynojirimycin (DNJ), in the mulberry leaf extract which acts as α-glucosidase inhibitor. Fruit snacks containing mulberry leaf extract were developed and the postprandial metabolic response against a reference (white bread matched for carbohydrate) will be observed.

Conditions

• Blood Glucose

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fruit snack 1	Fruit snacks with original level of sugar
DIETARY_SUPPLEMENT	Fruit Snack 2	Fruit snacks with original level of sugar and mulberry leaf extract
DIETARY_SUPPLEMENT	Fruit Snack 3	Fruit snacks with reduced level of sugar
DIETARY_SUPPLEMENT	Fruit Snack 4	Fruit snacks with zero added sugar
DIETARY_SUPPLEMENT	White Bread	White bread with matched carbohydrate as control

Timeline

• Start date: 2023-06-22
• Primary completion: 2023-10-31
• Completion: 2023-10-31
• First posted: 2023-07-27
• Last updated: 2024-06-07

Locations

1 site across 1 country: United States