Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05959291

Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer

Free-HER: Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
University of Miami · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this preliminary research study is to see if patients discontinuing maintenance Herceptin and/or other anti-HER-2 treatments with monitoring in addition to radiologic imaging and routine blood work will stay in complete radiological remission and to determine how long patients are able to stay in complete radiological remission without treatment.

Conditions

Interventions

TypeNameDescription
OTHERDiscontinuation of Anti-HER-2 Maintenance TreatmentPatients assigned to this group will be asked to discontinue anti-HER-2 maintenance treatment.

Timeline

Start date
2023-07-17
Primary completion
2026-07-31
Completion
2029-07-31
First posted
2023-07-25
Last updated
2025-08-13

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05959291. Inclusion in this directory is not an endorsement.