NCT05958641

Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents

Early Warning Model Construction on Cognition, Resistance and Using Risk of the New Psychoactive Substances in Adolescents Based on Behavioral Expression of Addiction Susceptibility Genes and Adverse Childhood Experience

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Wei XIA, PhD · Academic / Other
• Sex: All
• Age: 14 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old. This study intends to obtain the data related to the behavioral expression of addiction susceptibility genes, adverse childhood experience, cognition, resistance and the use of NPS in adolescents by questionnaire survey (sample size: 200), and then use logistic regression and machine learning to construct an early warning model.

Detailed description

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model on the use of the New Psychoactive Substances using for adolescents aged 14-35 years old. This study intends to conduct a questionnaire survey (sample size 200) to obtain data related to the behavioral expression of addiction susceptibility genes, childhood adversity experience, cognition, resistance and the use of NPS in adolescents from different regions and different populations. Through data analysis, this study aims to get the weight of different risk factors on NPS use, and then use logistic regression and machine learning to construct an early warning model, so as to screen out high-risk groups. At the same time, the expert group was consulted to establish a risk early warning system to provide a basis for intervention.

Conditions

• Drug Addiction

Interventions

Type	Name	Description
OTHER	Questionnaires	Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.

Timeline

• Start date: 2023-07-17
• Primary completion: 2023-10-31
• Completion: 2023-11-30
• First posted: 2023-07-24
• Last updated: 2023-07-24

Locations

1 site across 1 country: China