NCT05954624

Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid

A Open-Label, Two-sequence Phase I Drug-drug Interaction Clinical Study to Investigate the Pharmacokinetics of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid in Healthy Participants

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Guangdong Raynovent Biotech Co., Ltd · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The drug-drug interaction study had been designed to investigate the effect of ZSP1273 on the pharmacokinetics of digoxin, Rosuvastatin and the effect of Itraconazole and Probenecid on the pharmacokinetics of ZSP1273

Conditions

• Drug Drug Interaction

Interventions

Type	Name	Description
DRUG	Digoxin	oral
DRUG	Rosuvastatin	oral
DRUG	ZSP1273	oral
DRUG	Itraconazole	oral
DRUG	Probenecid	oral

Timeline

• Start date: 2023-07-10
• Primary completion: 2023-11-20
• Completion: 2023-11-30
• First posted: 2023-07-20
• Last updated: 2024-01-29

Locations

1 site across 1 country: China