Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05953519

Meeting an Unmet Need in Multiple Sclerosis

Meeting an Unmet Need in Multiple Sclerosis (MS): An Evaluation of the Effectiveness of a Transdiagnostic Psychological Treatment and Its Outcomes

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Kessler Foundation · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objectives of this study is to examine the efficacy of the Unified Protocol in decreasing depression and anxiety among individuals with MS and the secondary outcomes (e.g., improved well-being, QOL, coping, etc.) that may occur in tandem.

Detailed description

The primary objectives of this study is to examine the efficacy of the Unified Protocol in decreasing depression and anxiety among individuals with MS and the secondary outcomes (e.g., improved well-being, QOL, coping, etc.) that may occur in tandem. To achieve this, the investigation has the following specific aims: Specific Aim 1: Conduct a pilot Randomized Controlled Trial (RCT) of the Unified Protocol among individuals with MS to determine the effectiveness of the intervention in reducing depression and anxiety. Hypothesis 1: Individuals who participate in the Unified Protocol intervention will report a decrease in their depression and anxiety compared to individuals in the control group. Specific Aim 2: Conduct a pilot RCT of the Unified Protocol among individuals with MS to determine the effectiveness of the intervention in improving secondary outcomes of psychological well-being, QOL, coping, and MS symptomatology over time. Hypothesis 2: Individuals who participate in the Unified Protocol intervention will report an increase in psychological well-being, QOL, coping, and MS symptomatology over time compared to participants in the control group.

Conditions

Interventions

TypeNameDescription
BEHAVIORALUnified ProtocolThe Unified Protocol is a transdiagnostic intervention developed to treat depression and anxiety.

Timeline

Start date
2023-04-10
Primary completion
2025-04-30
Completion
2026-04-30
First posted
2023-07-20
Last updated
2023-07-20

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05953519. Inclusion in this directory is not an endorsement.