NCT05953311

Neurological Blood-based Biomarkers and Cognitive Disorders in Critically Ill Survivors.

The Relationship Between Neurological Blood-based Biomarkers and Mid-term Cognitive Disorders in Critically Ill Survivors.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Cognitive disorders are common after intensive care. Currently, their diagnosis is based on clinical tests. The investigators plan to study the relationship between different neurological blood biomarkers (cytokines, S100β protein, neuron specific enolase, total Tau protein and neurofilament light chain) and the occurrence of cognitive disorders during the three months following intensive care discharge.

Conditions

• Intensive Care Unit Syndrome
• Post-intensive Care Syndrome
• Cognitive Disorder

Interventions

Type	Name	Description
OTHER	Blood analysis	Blood analysis for neurological biomarkers measurements
OTHER	Cognitive tests	Questionnaires assessing cognitive function

Timeline

• Start date: 2023-06-23
• Primary completion: 2025-06-30
• Completion: 2025-12-31
• First posted: 2023-07-20
• Last updated: 2023-07-20

Locations

1 site across 1 country: Belgium