NCT05947981

Pre-operative 5% Dextrose Infusion & PONV

Is Pre-operative Infusion of 5% Dextrose Effective in Reducing the Incidence of PONV in Middle Ear Surgery? A Blinded Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

With this study, we aim to compare the efficacy of pre-operative dextrose-containing fluid infusion with other fluid for the prevention of PONV in middle ear surgeries.

Detailed description

We hypothesized that maintenance of stable level of blood glucose in addition to adequate hydration through preoperative intravenous dextrose 5% infusion will have a rule in decreasing the incidence and severity of PONV; as it reduces insulin resistance and decreases gastric acid secretion; which may contribute to PONV.

Conditions

• Nausea, Postoperative

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dextrose 5%, normal saline	Decrease fasting hours

Timeline

• Start date: 2023-10-01
• Primary completion: 2024-01-31
• Completion: 2024-01-31
• First posted: 2023-07-17
• Last updated: 2024-03-27

Locations

1 site across 1 country: Egypt