NCT05947305

Alternative Gingival De-Epithelialization Techniques

Alternative Gingival De-Epithelialization Techniques: A Randomized Controlled Trial

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare different de-epithelialization methods in patients undergoing soft tissue augmentation surgery. The main questions it aims to answer are: • Which technique is superior for de-epithelialization in terms of remaining epithelium, wound healing of the donor site, and clinical outcomes?

Detailed description

Participants will be randomly assigned to one of four surgical techniques during their surgical procedure and the wound site will be assessed on post-operative days 1, 7, 14, and 21. Researchers will compare the use of mucotome, Er:YAG laser, surgical diamond bur, or blade to observe patterns of wound healing and assess if one method is superior in terms of removing the epithelium.

Conditions

• Recession, Gingival
• Surgical Procedure, Unspecified
• Graft Complication
• Wound Heal

Interventions

Type	Name	Description
PROCEDURE	Surgical Blade	Using a 15c blade to de-epithelialize the soft tissue extra-orally
PROCEDURE	Mucotome	Using Megagen Mucotome to de-epithelialize the soft tissue intra-orally
PROCEDURE	Diamond Bur	Using a surgical diamond bur to de-epithelialize the soft tissue intra-orally
PROCEDURE	Er:YAG Laser	Using an Er:YAG Laser to de-epithelialize the soft tissue intra-orally

Timeline

• Start date: 2024-04-04
• Primary completion: 2026-06-30
• Completion: 2026-07-01
• First posted: 2023-07-17
• Last updated: 2026-01-16

Locations

1 site across 1 country: United States