NCT05945654

Functional Outcome After Anastomotic Leak After Oesophagectomies

Subjective Functional Outcome After Oesophagectomy With and Without Anastomotic Leak

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Stefan Gutknecht · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main surgical treatment for oesophageal cancer is a curative resection, mostly performed according to Ivor Lewis. However, despite careful work and refined surgical techniques, anastomotic leakage (AL) occurs in more than 1/10 of the patients. This severe complication normally requires immediate intervention, while over the last 10 years, endoscopic vacuum therapy (EVT) has become the crucial therapy for broken-down anastomosis. The hypothesis is that despite suffering a severe complication, the subjective swallow function is not impaired in patients treated by EVT after an anastomotic leak, compared to patients without AL.

Detailed description

The investigators will select patients after oesophagectomy and perform a structured interview regarding their quality of life and subjective swallow function. Results will be compared according to defined subgroups, especially patients with and without anastomotic leak.

Conditions

• Anastomotic Leak Esophagus
• Swallowing Disorder

Interventions

Type	Name	Description
PROCEDURE	Anastomotic Leak after Ivor Lewis Oesophagectomy	Surgical resection of the esophagus with oesophagogastrostomy. Groups depend on postoperative complication

Timeline

• Start date: 2023-09-01
• Primary completion: 2024-01-31
• Completion: 2024-02-28
• First posted: 2023-07-14
• Last updated: 2023-07-14

Locations

1 site across 1 country: Switzerland