Trials / Completed
CompletedNCT05944198
Clinical Study of 18F-FAPI-RGD PET/CT in Rheumatoid Arthritis
Clinical Study of 18F-labeled Probes Targeting Fibroblast Activating Protein and Integrin avβ3 (FAPI-RGD) to Assess Disease Activity in Rheumatoid Arthritis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (actual)
- Sponsor
- Sichuan Provincial People's Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The goal of this observational study is to learn about 18F-FAPI-RGD PET/CT imaging in assessing rheumatoid arthritis disease activity. Participants will undergo clinical evaluation and 18F-FAPI-RGD PET/CT examination.
Detailed description
Patients with rheumatoid arthritis who met the 2010 American College of Rheumatology/European League against Rheumatism Rheumatoid arthritis classification criteria will be included. All patients will be assessed for disease activity and the clinical disease activity Index (cDAI) was calculated. Blood sedimentation rate and CRP assay results will be collected. All patients will undergo 18F-FAPI-RGD PET/CT examination. The correlation of cDAI, ESR and CRP levels with PET joint count and PET joint index as measured by 18F-FAPI-RGD PET/CT will be statistically analyzed.
Conditions
Timeline
- Start date
- 2023-07-14
- Primary completion
- 2024-02-20
- Completion
- 2024-02-20
- First posted
- 2023-07-13
- Last updated
- 2024-07-15
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05944198. Inclusion in this directory is not an endorsement.