NCT05941728

Persea Americana for Total Health (PATH)-2

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: University of Illinois at Urbana-Champaign · Academic / Other
• Sex: All
• Age: 25 Years – 74 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn about the effects of avocado consumption on gastrointestinal health in adults with overweight and obesity. The main questions is aims to answer are: How does avocado consumption affect the gut microbiome? How does avocado consumption affect thinking? Are there connections between the microbiome and cognition? Participants will be asked to eat provided meals with and without avocados for three 4-week periods. At the end of each 4-week period, participants will be asked to provide stool samples and complete computer games that assess thinking and memory.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
OTHER	Avocado	The intervention treatment will contain avocado
OTHER	Oil + Fiber	The active comparator will contain a snack with oils and fibers that mimic an avocado
OTHER	Average American Diet	The sham comparator will contain foods/beverages that mimic a standard American Diet

Timeline

• Start date: 2023-07-11
• Primary completion: 2024-07-01
• Completion: 2024-07-01
• First posted: 2023-07-12
• Last updated: 2023-10-13

Locations

1 site across 1 country: United States