Trials / Active Not Recruiting
Active Not RecruitingNCT05939336
MOS Prebiotic Potential in Older Adults
The Prebiotic Potential of a Yeast Cell Wall Fraction Containing Mannooligosaccharides and β-glucans.
- Status
- Active Not Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- University of Florida · Academic / Other
- Sex
- All
- Age
- 50 Years – 99 Years
- Healthy volunteers
- Accepted
Summary
Mannooligosaccharides (MOS) derived from baker's yeast may have prebiotic properties such as improving gastrointestinal function. The aims of this study are to determine the effect of MOS on gastrointestinal function and symptoms and fecal microbiota in older adults.
Detailed description
Novel prebiotics with specific microbiome targets and without adverse gastrointestinal symptoms are needed for the exploration of health benefits. This is a 3-week, open-label pilot study designed to evaluate the effect of 15 g per day of yeast-derived mannooligosaccharides on gastrointestinal symptoms, stool frequency, fecal microbiome, and urinary metabolites.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Mannooligosaccharides yeast extract | 15 g per day of mannooligosaccharide yeast extract. |
Timeline
- Start date
- 2023-08-01
- Primary completion
- 2024-02-28
- Completion
- 2026-06-30
- First posted
- 2023-07-11
- Last updated
- 2026-01-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05939336. Inclusion in this directory is not an endorsement.