NCT05938062

Fibrinogen Concentrate and Placenta Acreta Spectrum

Is the Use of Fibrinogen in Cesarean Section Related to Bleeding and Blood Product in Patients With Placenta Accreta Spectrum?: a Retrospective Randomized Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 146 (actual)
• Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Other Government
• Sex: Female
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS. The key question(s) it aims to answer are: \[Does the use of fibrinogen concentrate reduce bleeding in PAS patients?\] Patients who had a cesarean section with a pre-diagnosis of PAS were analyzed retrospectively. The choice of anesthesia applied to the patients and the relationship between the use of blood products and bleeding were evaluated.

Detailed description

Our study was designed as a retrospective randomized study. Patients aged 20-50 years and \>34 weeks of gestation who accepted the birth with a cesarean section with a pre-diagnosis of PAS were evaluated retrospectively. examined. were randomized into 2 groups, 53 patients in each group: group1: GNF : the group without fibrinogen concentrate Group 2: GF: the group with fibrinogen concentrate

Conditions

• Obstetric Anesthesia Problems
• Placenta Accreta

Interventions

Type	Name	Description
PROCEDURE	the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)	the group without fibrinogen concentrate (GNF, ) the group with fibrinogen concentrate (GF)

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-10-01
• Completion: 2023-05-01
• First posted: 2023-07-10
• Last updated: 2023-08-02

Locations

1 site across 1 country: Turkey (Türkiye)