NCT05937503

Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain

Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain.A Randomized Controlled Study.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Atılım University · Academic / Other
• Sex: All
• Age: 20 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Central sensitization (CS) is defined as the increased responsiveness of nociceptive neurons in the central nervous system to normal or subthreshold afferent input. CS has been proposed as an underlying mechanism of chronic pain in musculoskeletal disorders including low back pain (LBP). The aim of this study is to investigate the effect of manual therapy on central sensitization in patients with nonspecific chronic LBP.

Detailed description

A total of 40 LBP patients aged between 24-64 with CSS will be randomized into two groups. The manual therapy group will receive a 4-week manual therapy (two sessions/week) plus the conventional physiotherapy program, while the control group will only receive conventional physiotherapy. Before and after the interventions pain intensity (VAS), and scores of three questionnaires: Oswestry Disability Index (ODI), Central Sensitization Inventory (CSI), and the 36-item Short Form Health Survey Questionnaire (SF-36) will be recorded.The outcomes of the study will be analyzed by appropriate statistical methods.

Conditions

• Central Sensitization
• Manual Therapy

Interventions

Type	Name	Description
OTHER	manual therapy	The manual therapy group will receive a 4-week manual therapy plus conventionel physiotherapy.
OTHER	conventional physiotherapy	Control group will only receive conventionel physiotherapy intervention.

Timeline

• Start date: 2023-07-17
• Primary completion: 2023-08-30
• Completion: 2023-08-30
• First posted: 2023-07-10
• Last updated: 2023-07-18

Locations

2 sites across 1 country: Turkey (Türkiye)