Clinical Trials Directory

Trials / Completed

CompletedNCT05936749

Pre-implantation Genetic Testing for Monogenic Disease: Single Center Experience

Status
Completed
Phase
Study type
Observational
Enrollment
76 (actual)
Sponsor
Istituto Clinico Humanitas · Academic / Other
Sex
Female
Age
34 Years – 42 Years
Healthy volunteers

Summary

This monocentric retrospective observational study aims to evaluate the efficacy of pre-implantation genetic testing for monogenic diseases (PGT-M). The effectiveness will be assessed in terms of live birth rate (LBR), cumulative live birth rate (CLBR) per couple, and abortion rate (AR). Considering how many cycles the participants have undergone to achieve a viable blastocyst. The secondary objective is to evaluate the incidence of aneuploidy in unaffected embryos, in order to understand the need for pre-implantation genetic testing for aneuploidy (PGT-A)in addition to PGT-M.

Conditions

Interventions

TypeNameDescription
GENETICPre-implantation genetic testing

Timeline

Start date
2016-01-02
Primary completion
2022-12-12
Completion
2022-12-12
First posted
2023-07-10
Last updated
2023-07-10

Source: ClinicalTrials.gov record NCT05936749. Inclusion in this directory is not an endorsement.