NCT05935930

Postoperative Effects of Propofol Versus Sevoflurane Anesthesia

Postoperative Effects of Propofol Versus Sevoflurane Anesthesia During Elective Non-Cardiac Surgeries. A Randomized Clinical Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Damanhour Teaching Hospital · Other Government
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Background: The choice of appropriate anesthetics is essential to protect brain function, decrease perioperative complications, and provide high-quality care, and better quality of life. Objectives: To compare the efficacy and safety of propofol versus sevoflurane in patients undergoing elective, non-cardiac operations under general anesthesia. Methods: This was a randomized (1:1), parallel, phase four clinical trial; carried out on 44 patients, who were candidates for elective, non-cardiac operations under general anesthesia at our hospital. Patients were randomly allocated into two equal groups in which anesthesia was maintained with propofol infusion in group P and sevoflurane inhalation in group S.

Conditions

• General Anesthetic Drug Adverse Reaction

Interventions

Type	Name	Description
DRUG	Propofol 10 MG/ML Injection	Propofol infusion
DRUG	Sevoflurane Inhalation Liquid	Sevoflurane inhalation

Timeline

• Start date: 2021-12-01
• Primary completion: 2024-12-15
• Completion: 2024-12-15
• First posted: 2023-07-07
• Last updated: 2025-02-05

Locations

1 site across 1 country: Egypt