NCT05934474

Biocollection on Peripheral Inflammation

Biocollection on Peripheral Inflammation in Psychiatric Pathologies

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Most psychiatric research is based on the nosographic classifications used in current practice. At present, there is no diagnostic or prognostic biomarker for psychiatric pathologies commonly used in clinical practice. The study hypothesis is that peripheral inflammatory biomarkers could be common to several psychiatric disorders, in particular psychotic disorders (bipolar disorder, schizophreniform disorder, schizophrenia, depressive episode with psychotic features). The aim of this project is to set up a bio-collection of biological samples (peripheral blood samples) with associated phenotypic data (assessment of various symptoms using standardized scales in patients whose blood is sampled). The setting up of this cohort follows on from work carried out on a PsyCourse cohort also using a transdiagnostic approach in psychiatry, in order to be able to collaborate within a European research project.

Conditions

• Schizoaffective Disorder, Depressive Type
• Bipolar Disorder I
• Bipolar Disorder II

Interventions

Type	Name	Description
BIOLOGICAL	Peripheral venipuncture blood sampling, as part of standard care procedures	Collection of 36 mL of blood
OTHER	Interview with a psychiatrist	Research project data collection

Timeline

• Start date: 2024-03-19
• Primary completion: 2026-08-02
• Completion: 2028-02-02
• First posted: 2023-07-07
• Last updated: 2024-04-08

Locations

1 site across 1 country: France