NCT05933135

Factor XIII Activity in Gastrointestinal Bleedings

Influence of Factor XIII Activity on the Outcome of Gastrointestinal Bleedings

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 97 (actual)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The aim of this retrospective study is to investigate the relationship between factor XIII activity and the outcome of gastrointestinal bleedings. Since factor XIII is of great importance in haemostasis and plays a key role in stabilizing the fibrin clot, it can be assumed that a deficiency of factor XIII leads to an unfavorable course of gastrointestinal bleedings. Our hypothesis is that early detection of such a deficiency can prevent a more severe course and that substitution of factor XIII contributes to faster cessation of bleeding, improves patient outcome and reduces the number of red cell concentrates required.

Conditions

• Gastro Intestinal Bleeding

Interventions

Type	Name	Description
DRUG	Factor XIII Injection	Patients could have had an Factor XIII Injection in clinical routine

Timeline

• Start date: 2021-01-08
• Primary completion: 2022-12-31
• Completion: 2023-12-31
• First posted: 2023-07-06
• Last updated: 2025-03-25

Locations

1 site across 1 country: Austria