NCT05931237

Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults

Evaluation of the Inter-individual Variability Associated With the Interaction Between Flavan-3-ols From Cranberry and Gut Microbiota - an Exploratory Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 39 (actual)
• Sponsor: Laval University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability. The objective of this pilot study is to characterize the inter-individual variability associated with the interaction of (poly)phenols from cranberry and gut microbiota. The participants (n=39) of this study are healthy adults aged between 23 and 63 years old and consumed cranberry extract rich in (poly)phenols for 4 days. Plasma, urine and feces were collected to quantify gut microbial (poly)phenols metabolites and to profile the fecal microbiota.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cranberry extract capsules	Cranberry extract capsules (Prebiocran(TM))

Timeline

• Start date: 2021-09-09
• Primary completion: 2021-11-19
• Completion: 2021-11-19
• First posted: 2023-07-05
• Last updated: 2023-07-05

Locations

1 site across 1 country: Canada