Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05927428

Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

An Open-Label, Multi-Center, Phase 2 Dose Ranging Study of BRM424 Ophthalmic Solution in Patients With Neurotrophic Keratitis (NK)

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
12 (estimated)
Sponsor
BRIM Biotechnology Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to obtain initial efficacy of BRM424 in patients with Stage 2 and Stage 3 NK and evaluate safety and tolerability.

Conditions

Interventions

TypeNameDescription
DRUGBRM424 Ophthalmic Solution - Dose1A topical drop of BRM424 ophthalmic solution.
DRUGBRM424 Ophthalmic Solution - Dose2A topical drop of BRM424 ophthalmic solution.

Timeline

Start date
2024-07-31
Primary completion
2025-08-30
Completion
2025-11-30
First posted
2023-07-03
Last updated
2024-10-28

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05927428. Inclusion in this directory is not an endorsement.