Trials / Completed
CompletedNCT05927103
Differences Between Coffee and Non-coffee Drinkers in the Gut Microbiome and Microbiota-Gut-Brain Axis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 62 (actual)
- Sponsor
- University College Cork · Academic / Other
- Sex
- All
- Age
- 30 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to investigate the potential of coffee to act as a prebiotic to alter gut microbiota and improve mood, memory and cognitive performance.
Detailed description
The aim of this study is to investigate the potential of coffee to act as a prebiotic to alter gut microbiota and improve mood, memory and cognitive performance in moderate coffee drinkers compared to non-coffee drinkers healthy adults. Reaction time, socioemotional processing, visual and episodic memory, learning, and an attentional task were administered to measure cognitive performance. Self-report questionnaires on mood, behavior and lifestyle were administered and response to an acute stressor was assessed. Biological samples of saliva, urine, blood, and stool were collected to investigate microbiome-gut-brain-axis signaling such as inflammation, short chain fatty acids and other metabolites production and physiological stress.
Conditions
Timeline
- Start date
- 2021-09-21
- Primary completion
- 2023-01-18
- Completion
- 2023-01-18
- First posted
- 2023-07-03
- Last updated
- 2023-07-03
Locations
1 site across 1 country: Ireland
Source: ClinicalTrials.gov record NCT05927103. Inclusion in this directory is not an endorsement.