NCT05925465

Maxillary and Mandibular Nerve Block

Effect of Combined Maxillary and Mandibular Nerve Block on Orthognathic Surgery Outcomes

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Mandibular fractures are among the most common (60-70%) maxillofacial fractures observed in emergency rooms. In the closed reduction (non-surgical), the bone fragments are realigned manually or by using traction devices. The open reduction surgery of mandibular fractures should first ensure the restoration of the occlusion of the mandible to prevent postoperative malocclusion, followed by stabilization by means of rigid fixations such as plates, screws, and rigid intermaxillary blocks in order to minimise any nonunion, malunion, or delayed union of the fracture segments. These surgical procedures are associated with moderate postoperative pain, being the first 24 hours the most intense pain period. Maxillary and mandibular nerve blocks are performed in patients with refractory trigeminal neuralgia. However, there have been few studies evaluating the analgesic effects of these blocks for maxillofacial surgeries.

Conditions

• Analgesia

Interventions

Type	Name	Description
PROCEDURE	Maxillary and mandibular nerve block	receive bilateral combined maxillary and mandibular nerve block
OTHER	Control	not receive any nerve block

Timeline

• Start date: 2023-08-01
• Primary completion: 2027-12-28
• Completion: 2028-03-31
• First posted: 2023-06-29
• Last updated: 2026-02-17

Locations

1 site across 1 country: Egypt