Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05924750

A Study of BL-M11D1 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

A Phase I Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BL-M11D1 in Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients

Status
Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
130 (estimated)
Sponsor
Sichuan Baili Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Ia: To observe the safety and tolerability of BL-M11D1 in patients with relapsed/refractory acute myeloid leukemia to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of BL-M11D1. Ib: Further observe the safety and tolerability of BL-M11D1 at the recommended dose in phase Ia to determine the recommended dose in phase II clinical study (RP2D).

Conditions

Interventions

TypeNameDescription
DRUGBL-M11D1Administration by intravenous infusion

Timeline

Start date
2023-08-02
Primary completion
2026-12-01
Completion
2027-12-01
First posted
2023-06-29
Last updated
2025-09-26

Locations

8 sites across 1 country: China

Source: ClinicalTrials.gov record NCT05924750. Inclusion in this directory is not an endorsement.