Clinical Trials Directory

Trials / Completed

CompletedNCT05922891

Tezepelumab PRO Study

Effectiveness of Tezepelumab on Asthma Control and Cough: A Prospective, Multi-center, Observational Study

Status
Completed
Phase
Study type
Observational
Enrollment
92 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 130 Years
Healthy volunteers
Not accepted

Summary

This study assesses the impact of tezepelumab treatment not only on asthma control but also on cough specific Health-Related Quality of Life (HRQoL). Asthma control can be evaluated using Asthma Control Questionnaire (ACQ). Cough symptom which is one of the symptoms related airway hyperresponsiveness can be assessed via the relevant questionnaire, Leicester Cough Questionnaire (LCQ). There is moderate negative correlation between ACQ and LCQ . Improvements in both asthma control and cough symptom by tezepelumab would clarify effectiveness of Tezepelumab in real-world. Though Tezepelumab is recently approved in Japan, there is no real-world evidence on tezepelumab, particularly on above mentioned symptoms. Thus, this study aims to estimate effectiveness of tezepelumab on asthma and cough symptoms in real world settings.

Conditions

Timeline

Start date
2023-09-27
Primary completion
2025-09-20
Completion
2025-09-20
First posted
2023-06-28
Last updated
2025-09-30

Locations

29 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT05922891. Inclusion in this directory is not an endorsement.