NCT05921955

Application of High-flow Nasal Oxygen in Cesarean Section

Effect of Maternal Oxygen Supplementation by High-flow Nasal Oxygen Compared With Room Air on Fetal Acidemia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Beijing Tongren Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The study propose that the using the high-flow nasl oxygen to provide oxygen for maternal can improve the fetal acidemia and the neonatal outcomes during cesarean section with combined spinal-epidural anesthesia.

Detailed description

Maternal oxygen supplementation is widely used intrauterine resuscitation technique in clinical, which can improve fetal oxygenation and prevent fetal acidemia. The incidence of hypotension is high in cesarean section with combined spinal-epidural anesthesia. Hypotension contributes to insufficient perfusion of uterus and placenta, resulting in decreased fetal oxygen supply and neonatal acidemia. High flow nasal oxygen have a better improvement oxygenation of patients by providing high flow oxygen airflow with heating and humidification through nasal cannula.

Conditions

• Fetal Acidemia

Interventions

Type	Name	Description
DEVICE	Optiflow high-flow nasal cannula system	Using the Optiflow high-flow nasal cannula system to supply oxygen for maternal.

Timeline

• Start date: 2023-07-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2023-06-27
• Last updated: 2024-01-26

Locations

1 site across 1 country: China