NCT05921695

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Patients With Heat Stroke

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 190 (estimated)
• Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare the effect of high chlorine solution such as normal saline and non-high chlorine solution such as sodium lactate ringer's solution on renal function in patients with heat stroke. The main question it aims to answer is whether limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke. Participants will receive a free normal saline infusion during the emergency department according to the study design, or a restricted normal saline infusion while using sodium lactate Ringer's instead. Researchers will compare the normal saline infusion group and sodium lactate Ringer's group to see if limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke.

Conditions

• Heat Stroke

Interventions

Type	Name	Description
DRUG	Normal Saline infusion and Ringer lactate infusion	The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.

Timeline

• Start date: 2023-05-28
• Primary completion: 2025-10-01
• Completion: 2026-03-01
• First posted: 2023-06-27
• Last updated: 2024-09-20

Locations

7 sites across 1 country: China