NCT05921071

Do Patients Who Received Tranexamic Acid in Vaginal Hysterectomy Loose Les Blood, Comparing to Patients Who Did Not?

Do Patients Who Are Treated With Tranexamic Acid Loose Les Blood, Comparing to Patients Who Are Not Treated, During Vaginal Hysterectomy? a Randomized Control Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Wolfson Medical Center · Other Government
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This is a randomized control, double-blind study in which women who are about to go an elective vaginal hysterectomy are offered to participate. Patients will be randomly assigned to one of two groups: the tranexamic acid group, in which 1 gram of tranexamic acid (Hexakapron) is administered intravenously before surgery, and the control group, in which patients will receive 10 ml of normal saline 0.9% intravenously.

Detailed description

This is a randomized control, double-blind study in which women who are about to go for an elective vaginal hysterectomy are offered to participate. Patients will be randomly assigned to one of two groups: the tranexamic acid group, in which 1 gram of tranexamic acid (Hexakapron) is administered intravenously before surgery, and the control group, in which patients will receive 10 ml of normal saline 0.9% intravenously. A nurse will prepare the solution according to the randomization and will handle it to the anesthesiologist.

Conditions

• Vaginal Hysterectomy

Interventions

Type	Name	Description
DRUG	Tranexamic acid	One gram of tranexamic acid (Hexakapron) is administered intravenously before surgery
DRUG	Placebo	patients will receive 10 ml of normal saline 0.9% intravenously.

Timeline

• Start date: 2023-01-22
• Primary completion: 2024-06-01
• Completion: 2025-01-01
• First posted: 2023-06-27
• Last updated: 2024-04-23

Locations

1 site across 1 country: Israel