NCT05920642

Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture

Risk-benefit Analysis of Intrathecal Morphine Administration to Patients Undergoing Surgical Treatment of Proximal Femoral Fracture (Monocentric, Single-blinded, Randomized Clinical Study Compared to Standard Treatment)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 82 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: All
• Age: 60 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to investigate postoperative pain relief for patients undergoing surgical treatment of proximal femoral fracture using intrathecal administration of morphine.

Detailed description

In this study, the investigators will compare the efficiency of intrathecal morphine administration with the standard of care (parenteral application of analgesics) for pain relief in patients after proximal femoral fracture surgery. The secondary outcome measure will be to determine the frequency of adverse effects of intrathecally administered morphine. The study will be monocentric, randomized, and single-blinded. A total of 50 patients are expected to be enrolled.

Conditions

• Proximal Femur Fracture

Interventions

Type	Name	Description
DRUG	Intrathecal morphine administration	Administration of morphine into the spinal canal.
DRUG	Parenteral administration of analgesics	Standard postoperative pain management of analgesics using parenteral route of administration.

Timeline

• Start date: 2023-09-04
• Primary completion: 2025-07-29
• Completion: 2025-07-29
• First posted: 2023-06-27
• Last updated: 2025-11-25

Locations

1 site across 1 country: Czechia